Generic Retinoid for RET-Fusion NSCLC

So, Selpercatinib is this special kind of drug that targets a protein called RET. It’s used to treat certain types of lung cancer, thyroid cancer, and other cancers where RET is changed. It’s made to stop this thing called RET kinase from doing its thing.

You can get this drug in two sizes, either 40 mg or 80 mg, and they come in capsule form. For grown-ups, the usual dose is 160 mg, and you take it twice a day. You can have it with or without food, no problem.

It comes in bottles with 60 capsules in each one. You need a doc to manage your treatment, and you’ve got to take these capsules whole, no chewing or breaking them open. The main stuff in the drug is like a bouncer for this RET protein that gets all wonky in cancer.

They came up with the dose after doing studies that showed it works and is safe for people with these RET changes in their tumors.