$100 120mg HIF-2α inhibitor for VHL RCC

Belzutifan is used for treating VHL-associated renal cell carcinoma, or RCC. It’s like a pseudo-inhibitor for HIF-2α, which lessens the signal that tumors send out during low oxygen conditions. The pills are given in 40 milligram doses, but you take 120 mg of them a day.

You can buy this stuff in a bottle with 90 tablets that have a coating. It’s made for a particular kind of kidney cancer, with VHL being associated with it, and you take 120 mg of it, just once every 24 hours. These come as 40 mg pills, and they usually come in a batch of 90, which is pretty handy for patients.

It works by keeping HIF-2α, that’s part of the HIF-1 thing, from doing its thing, which is telling cells when there’s not much oxygen around.